These take pre-created playlists and evenly shuffle them together into a new playlist. You can make a "battle of the bands" playlist, alternating between bands. You can shuffle 5 genres (for example, Jazz-Country-Rock-Folk-Metal) so that every 5th tune is a jazz tune. Perhaps you'd like to alternate between new tunes and old tunes, your wife's favorites and your favorites, etc. These scripts make this easy to do.
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Select iPod tracks in iTunes and add them to iTunes