From the comments at Chris Breen's What's new in iTunes 7.1 at Playlist:
One feature that undoubtedly escape[d] most peoples['] notice is [the] fact that iTunes is now accessible with VoiceOver. This is a major step forward for sight impaired individuals. In the past VoiceOver could not access anything within iTunes. Now virtually everything in iTunes can be navigated and controlled with VoiceOver....Kudos go to Apple for getting iTunes accessible.